Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Unauthorized use of these marks is strictly prohibited. Common metronidazole side effects may include: depression, trouble sleeping, feeling irritable; nausea, vomiting, loss of appetite, stomach pain; vaginal itching or discharge, pain during sex; This is not a complete list of side effects and others may occur. Treatment is with an antifungal mouthwash such as nystatin or oral antifungal tablets or capsules. There needs to be more research done investigating this potential interaction, but because doctors are unable to say which people are more at risk of this interaction, it is best to err on the side of caution and avoid alcohol while taking metronidazole until more is known. Cryptosporidiosis is a highly prevalent gastrointestinal parasitic disease caused by protozoan species of the genus Cryptosporidium that infect a wide range of animals, including people, throughout the world. Metronidazole is the treatment of choice. This limitation of treatment options presents a major public health challenge given the important burden of disease. Young children and pregnant women may be more susceptible to dehydration resulting from diarrhea and should drink plenty of fluids while ill. a blood thinner - warfarin, Coumadin, Jantoven. Saving Lives, Protecting People, Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-Exposed and HIV-Infected Children, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Foodborne, Waterborne, and Environmental Diseases (DFWED), General Information for Immunocompromised Persons, Prevention & Control Immunocompromised Persons, Prevention & Control Childcare Facilities, Responding to Crypto Outbreaks at Childcare Facilities, Hospitals, Healthcare Facilities, & Nursing Homes, A Guide to Commercially-Bottled Water and Other Beverages, Information for Immunocompromised Persons, Information for Public Health & Medical Professionals, Water, Sanitation, & Environmentally-related Hygiene, U.S. Department of Health & Human Services. Nitazoxanide was synthesized in the 1980s by combining a thiazole ring (similar structurally to metronidazole) with a benzamidine ring (similar to the tapeworm drug niclosamide). It causes watery diarrhea that can be severe. Children between 1 and 4 are the most likely to get cryptosporidiosis. Cryptosporidiosis is occasionally seen in amphibian species and is typically caused by Cryptosporidium fragile , an apicomplexan protozoa. A Cryptosporidium infection can become chronic if you have a weakened immune system. In June 2004, nitazoxanide was also licensed for older children and adults. Dont swim if you have diarrhea. Ideally it is best to treat all shelter animals with a single all-purpose dewormer that is inexpensive, safe, convenient to administer, highly effective against a broad spectrum of parasites, and appropriately labeled for the intended use. Most people with healthy immune systems will get better without treatment for cryptosporidiosis. Symptoms of a yeast infection include itching and a thick, white odor-free discharge and it can be easily treated with medication such as fluconazole. If you use a breast pump during this time, throw out the milk and do not feed it to your baby. Incidence of Cryptosporidium spp. CDC twenty four seven. Do not use metronidazole to treat any condition that has not been checked by your doctor. Tell your doctor about all your current medicines. Cryptosporidium spp. Continue reading. While initially reported in immunocompromised such as AIDS patients, cryptosporidiosis has now been documented as a major cause of childhood diarrhea and an important factor in childhood malnutrition. The schedule may depend on the exact dosage form or strength of the medication. You may have unpleasant effects such as headaches, nausea, vomiting, stomach cramps, and warmth or tingling under your skin. Metronidazole is an antimicrobial medication that has antiprotazoal . Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. There is a need for a highly effective treatment for cryptosporidiosis in immunodeficient patients, but the quest for such a drug has proven to be elusive. Parasitologic cure (no Cryptosporidium detected in stool) rates range from 60-75% 1. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Take metronidazole exactly as prescribed by your doctor. You should not use this medicine if you are allergic to metronidazole, secnidazole, or tinidazole, or if: you consumed foods or medicines that contain propylene glycol in the past 3 days; or. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. 2001 Jun 15;32(12):1792-4. doi: 10.1086/320751. Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available. Its important to take precautions to avoid infection with Cryptosporidium if youre: Pregnant people and infants are at higher risk of dehydration from diarrhea. Nitazoxanide: a new thiazolide antiparasitic agent. Expand current row for information about Alinia, Expand current row for information about nitazoxanide, Expand current row for information about Humatin, Expand current row for information about paromomycin. Predicting the emergence or disappearance of specific pathogensother than in the setting of an identified outbreakis difficult and has not significantly prevented or limited foodborne illnesses. Ask your provider what foods you should eat and which to avoid. Explore lung, breathing and allergy disorders, treatments, tests and prevention services provided by the Cleveland Clinic Respiratory Institute. Fenbendazole and metronidazole are effective against Giardia. MeSH The parasite can cause a gastrointestinal illness called cryptosporidiosis (crip-toe-spor-id-ee--sis). If you have an underlying condition that weakens you immune system, your provider will help you manage your underlying condition, which can help the symptoms of cryptosporidiosis. In animal studies (mice and rats), this medicine caused certain types of cancers or tumors. Print 2018 Apr. Intestinal and urogenital protozoa. It had previously been licensed in 2002 for only children aged 1-11 years. Pronunciation: me-troe-NI-da-zole A limited number of infectious agents account for most of these illnesses, raising the hope that advances in the treatment and prevention of these infections can have global health impact. 2018 Mar 27;62(4):e01505-17. Symptoms and time of onset can narrow the differential diagnosis (Table 3) and help identify a likely pathogen.4 Early onset of vomiting and diarrhea results from ingestion of preformed toxins, most often S. aureus or Bacillus cereus. Before . Empiric antibiotic therapy decreases the duration of symptoms in patients with traveler's diarrhea.5,9 Enterotoxigenic E. coli is the most common cause of traveler's diarrhea worldwide and is generally susceptible to ciprofloxacin, but azithromycin (Zithromax) is equally effective and a better choice in areas where fluoroquinolone-resistant C. jejuni is present.9,21 Patients with diarrhea of more than 10 days' duration that is associated with fatty or foul-smelling stools, cramps, bloating, and weight loss can be treated empirically for Giardia infection.22 Because of an increased risk of hemolytic uremic syndrome, patients receiving empiric antibiotic therapy should be monitored closely if Shiga toxinproducing E. coli infection is suspected.4,23, If empiric treatment has not been initiated, antibiotic therapy may be indicated once stool culture, bacterial toxin, or microscopy results are available. Empiric treatment should focus on symptom management, rehydration if the patient is clinically dehydrated, and antibiotic therapy. The views expressed in this article are those of the authors and do not necessarily reflect the official policy of the Department of Defense, the Department of the Army, or the U.S. Army Medical Department. When metronidazole is given as follow up treatment for persistent symptoms of chlamydia, usually in addition to other antibiotics such erythromycin, it is there to provide treatment for other possible bacterial causes that may cause similar symptoms to chlamydia. Fenbendazole (50 mg/kg bodyweight orally once daily for 3-5 We do not endorse non-Cleveland Clinic products or services. It is also very common in humans. However, the effectiveness of nitazoxanide in immunosuppressed individuals is unclear. Severe diarrhea can lead to life-threatening complications. It has a currently accepted medical use in treatment in the United States. Follow standard ChAMP guidelines where appropriate. Its very easy for cryptosporidiosis to spread from infected people or animals. This content is owned by the AAFP. Medications may also help cure a Cryptosporidium infection. Metronidazole is the drug of choice for treating giardiasis - but note cautions with pregnancy and breast-feeding. Bloody diarrhea with abdominal pain should prompt consideration of inflammatory damage to the intestinal mucosa or an infection (e.g., C. jejuni, Salmonella enteritidis, enteroinvasive E. coli) affecting the large bowel. Nitazoxanidehas been FDA-approved for treatment of diarrhea caused by Cryptosporidium in people with healthy immune systems and is available by prescription. 2023 Feb 24;18(2):e0281216. Consumer information on food safety is available from the CDC at http://www.cdc.gov/foodsafety/facts.html or from the U.S. Food and Drug Administration at http://www.fda.gov/Food/FoodborneIllnessContaminants/FoodborneIllnessesNeedToKnow/default.htm or http://www.foodsafety.gov, or by calling (888) SAFEFOOD ([888] 7233366). Mensah GT, Ayeh-Kumi PF, Annang AK, Owusu-Frimpong I, Niampoma S, Brown CA. Youre also at higher risk for getting cryptosporidiosis if you: If youre living with a compromised immune system and get cryptosporidiosis, youre at risk of ongoing and life-threatening illness. The .gov means its official. Childrenespecially infantsare predisposed to dehydration and require more diligence in determining hydration status. Some children have growth problems after having cryptosporidiosis. Drug classes: Amebicides, Miscellaneous antibiotics. While you may initially bring your symptoms to the attention of your family doctor, he or she may refer you to a gastroenterologist a doctor who specializes in digestive system disorders. Tell your doctor if you have symptoms such as itching or discharge during or after treatment with this medicine. You can review and change the way we collect information below. Cryptosporidiosis is diagnosed with a stool (poop) sample. While not effective against Cryptosporidium, nitroimidazoles such as metronidazole or tinidazole are effective treatments for giardiasis and can be administered as a single dose. (2013) reported that Paromomycin to be the more valuable than metronidazole for the treatment of Cryptosporidium infection in cattle based on the clinical trials. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. vomiting. MeSH Prevention is the first step in combatting foodborne illnesses. Not all possible drug interactions are listed here. For oral dosage forms (capsules or tablets): For amebiasis infections: Adults500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Centers for Disease Control and Prevention. Cryptosporidiosis is a diarrhoeal disease caused by the parasite, Cryptosporidium, which infects the intestine. Swallow the extended-release tablet whole and do not crush, chew, or break it. Keywords: You may need IV fluids or nutrition. nausea. Is not subject to the Controlled Substances Act. is a leading cause of diarrheal disease morbidity and mortality .Recent estimates suggest Cryptosporidium spp. For those persons with HIV/AIDS, anti-retroviral therapy that improves the immune status will also decrease or eliminate symptoms of cryptosporidiosis. Cryptosporidium goes through your mouth into your digestive system, where it reproduces and causes symptoms. cryptosporidium treatment metronidazole. Giardia duodenalis (C&D) trophozoites measure 9 to 21 long, 5 to 15 wide, and 2 to 4 thick. TREATMENT OF GIARDIASIS. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Orthostatic pulse and blood pressure changes should be noted, and a basic general physical examination should be performed, with assessment of skin turgor, the abdomen, mucous membranes, and mental status.5. However, the effectiveness of nitazoxanide in immunosuppressed individuals is unclear. The Centers for Disease Control and Prevention (CDC) estimates that one in six Americans (approximately 48 million) will become sick from a foodborne pathogen each year, resulting in 128,000 hospitalizations and 3,000 deaths.2 Most foodborne illnesses, hospitalizations, and deaths are caused by one of eight common pathogens: norovirus, nontyphoidal Salmonella, Clostridium perfringens, Campylobacter, Staphylococcus aureus, Toxoplasma gondii, Listeria monocytogenes, and Shiga toxinproducing Escherichia coli2 (Table 13). All information these cookies collect is aggregated and therefore anonymous. If your symptoms are mild, your doctor may recommend delaying treatment until after the first trimester or longer. FDA licensed nitazoxanide (Alinia, Romark Laboratories, Tampa, FL, USA) for treatment of cryptosporidiosis in children aged 1-11 years in November 2002. and transmitted securely. Cryptosporidium (cryptosporidiosis) . An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives. For many years the primary treatment for Giardia in dogs and cats has involved metronidazole. However, it is not effective in severely immunocompromised patients and there is limited data in infants. In patients with clinically significant vomiting, antiemetics can alleviate symptoms and reduce the need for hospitalization and intravenous fluid administration. Copyright 1996-2023 Cerner Multum, Inc. IV: Monitored (orange) antibiotic PLoS One. The Centers for Disease Control and Prevention estimates that each year, one in six Americans will experience a foodborne illness. Supportive treatment with fluids and nutritional supplementation may be necessary. The Marine Compound Tartrolon E Targets the Asexual and Early Sexual Stages of. Diarrhea within 24 to 48 hours of ingestion is most often caused by Campylobacter jejuni in individual cases or Salmonella in outbreaks.4 Foodborne illnesses commonly associated with fever are caused by Vibrio cholerae non-O1, Shigella, and C. jejuni (Table 4). McGraw Hill; 2018. https://accessmedicine.mhmedical.com. FOIA You should not breastfeed within 24 hours after using metronidazole. The gut microbiome composition changed significantly, and . None of the symptoms of foodborne illness is specific, so the clinician must consider the history, epidemiologic features, and objective findings to make an accurate diagnosis. But usually infection with cryptosporidium causes a gastroenteritis-type illness. Application of Proteomics to the Study of the Therapeutics and Pathogenicity of. In those who have weak immune systems, the focus of treatment is often on getting the immunity back. Multiple studies support the use of a single dose of ondansetron (Zofran) in children with gastroenteritis-related vomiting.1214 The use of antiemetics in adults with gastroenteritis is reasonable, but data about adverse effects are lacking. Epidemiology. Antiprotozoal medications stop protozoa like Cryptosporidium from growing in your body. Metronidazole is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. HIV-positive individuals who suspect they have cryptosporidiosis should contact their healthcare provider. Tinidazole, metronidazole. Metronidazole systemic 500 mg (PLIVA 334). First, it breaks alcohol down into a compound called acetaldehyde. This is because metronidazole not only kills the bacteria responsible for conditions such as bacterial vaginosis, but useful bacteria in the vaginal flora that help to keep other microbes in check. Oral rehydration therapy is effective in preventing and treating dehydration in patients of all ages. INTRODUCTION. Nitazoxanide in the treatment of cryptosporidial diarrhea and other intestinal parasitic infections associated with acquired immunodeficiency syndrome in tropical Africa. Disclaimer. PMC TIMOTHY L. SWITAJ, MD, KELLY J. You usually get it from contaminated water in public pools or other recreational swimming areas. Diagnosis and management of a foodborne illness are based on the history and physical examination. Editorial Note: Cryptosporidium is a protozoan parasite; it is a well recognized . Has a low potential for abuse relative to those in schedule 4. Iodoquinol or Metronidazole. Cloacal swabs were collected every 2 months for 6 months to measure C. serpentis shedding by probe . Acid fast stain - for Giardia & Cryptosporidium; Treatment of intestinal parasites. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Continue reading, If you are taking oral metronidazole or using metronidazole gel for an infection that is linked with sexual activity, such as trichomoniasis, pelvic inflammatory disease, or bacterial vaginosis you should not have sex for 7 days after single-dose therapy (or until you have completed the 7-day treatment regimen) and your symptoms have resolved. Empiric antibiotic therapy should be considered in cases of suspected foodborne illness if the patient is febrile and has signs of invasive disease, if symptoms have persisted for more than one week or are severe, or if hospitalization may be required. Protozoal Intestinal Infections and Trichomoniasis. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. in ducks was 39.9 % (365 out of 915 ducks). (https://pubmed.ncbi.nlm.nih.gov/24173771/). Version: 15.01. In: Harrison's Principles of Internal Medicine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. doi: 10.1371/journal.pntd.0010947. Foodborne illnesses should be reported to local and state health agencies; reporting requirements vary among states. Eat small bites of food if youre able to. Your provider will give you a sterile container and instructions on how to get a sample. Work with animals, particularly farm animals or livestock. The two most important parasitic causes of diarrheal disease are Cryptosporidium . Its estimated that there are over 700,000 cases of cryptosporidiosis in the U.S. each year. Data Sources: A PubMed search was completed using the key terms foodborne illness, infectious diarrhea, food poisoning, salmonella, Shigella, Escherichia coli, Campylobacter, food safety, hemolyticuremic syndrome, oral rehydration solution, oral rehydration therapy, traveler's diarrhea, and bloody diarrhea. Abuse may lead to severe psychological or physical dependence. Immunocompetent persons with cryptosporidiosis have been treated with multiple 3-day courses of nitazoxanide 5. Cryptosporidium is a protozoan parasite a one-celled organism that lives off of animals and people. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use metronidazole only for the indication prescribed. FOIA Ways to reduce your risk of getting and spreading cryptosporidiosis include: For most people, cryptosporidiosis is self-limiting, meaning it will go away on its own. Symptoms of cryptosporidiosis start two to 10 days after youre exposed to Cryptosporidium. Humatin. 2022 Nov 3:1-11. doi: 10.1007/s11259-022-10025-6. The reaction has been referred to as a disulfiram-like reaction disulfiram is a medication given to people to discourage alcohol consumption. Cryptosporidiosis is increasingly recognized as an important global health concern. stream Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. . Cryptosporidiosis is caused by the parasite Cryptosporidium. In: Loscalzo J, Fauci A, Kasper D, Hauser S, Longo D, Jameson J. eds. Teach children good hand washing hygiene at a young age. INTRODUCTION. Can metronidazole cause a yeast infection? It is presently not approved to treat immunodeficient persons because nitazoxanide oral suspension and nitazoxanide tablets have not been shown to be superior to placebo for the treatment of diarrhea caused by Cryptosporidium in HIV-infected or immunodeficient patients 1. All reports of outbreaks are entered into the CDC's Foodborne Disease Outbreak Surveillance System, after which the data are analyzed to monitor and identify the root cause of the outbreak. You also may be given instructions about how to bring in a sample of your stool. Has a high potential for abuse. Avoid getting water in your mouth if you swim in lakes, rivers or public pools. Copyright 2009. (Cryptosporidium . Metronidazole is active against anaerobic bacteria and some protozoa (e.g. Seven-day courses have also been used in early studies for cryptosporidiosis and other parasitic infections 6, 7. . New pathogens emerge constantly, whereas others decrease in significance or disappear altogether. https://www.uptodate.com/contents/search. Bessoff K, Spangenberg T, Foderaro JE, Jumani RS, Ward GE, Huston CD. Stool cultures are the diagnostic standard for bacterial foodborne illness; however, culture results are positive in less than 40% of cases. Identification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria box. Usually both sexual partners are treated at the same time, even if one has no symptoms. Abuse may lead to severe psychological or physical dependence. What happens if you drink alcohol with metronidazole? Metronidazole is usually given for up to 10 days in a row. Accessed Nov. 3, 2020. Stool tests may also be used to monitor the effectiveness of any treatment you receive. <> Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. You should stop using this medicine immediately if you experience any neurological symptoms such as seizures, headaches, visual changes, weakness, numbness, or tingling. Investigation of the prophylactic and therapeutic effectiveness of oral thyme extract in rats experimentally infected with cryptosporidium parvum. Supportive therapy is the key component in the management of cryptosporidiosis. 2022 Nov 15;10(11):2260. doi: 10.3390/microorganisms10112260. A single copy of these materials may be reprinted for noncommercial personal use only. Qin SY, Sun HT, Lyu C, Zhu JH, Wang ZJ, Ma T, Zhao Q, Lan YG, He WQ. In addition, it has anti-inflammatory properties in the large intestine and is an effective anti-diarrhea medication. Metronidazole is effective against Bacteroides fragilis, for example, which is a normal bacterial member of the gut and mouth microbiomes but can also be a culprit in wound infection, abscesses, chest infection (often associated with pneumonia), and liver infection. 8600 Rockville Pike Jumani RS, Bessoff K, Love MS, Miller P, Stebbins EE, Teixeira JE, Campbell MA, Meyers MJ, Zambriski JA, Nunez V, Woods AK, McNamara CW, Huston CD. This can result in an . Disulfiram blocks the effects of this enzyme which leads to acetaldehyde accumulation causing symptoms such as skin redness, palpitations, nausea, vomiting, headache and in severe cases a dangerous rapid heart rate or a sudden drop in blood pressure. Search date: March 2014. Although reporting requirements vary, most states require physicians to report cases of hepatitis A and botulism, and Salmonella, Shiga toxinproducing E. coli, Listeria, Shigella, and Vibrio infections. Next, the body reduces acetaldehyde to acetate using an enzyme called aldehyde dehydrogenase. Cryptosporidiosis spreads easily. Site of Infection and Pathogenesis. is responsible for approximately 7.6 million cases and between 48 000 and 202 000 deaths annually among young children in low-resource settings.Beyond acute morbidity and mortality, both symptomatic and . Discussion. The first group received 360 mg/kg paromomycin twice weekly in a food item for 6 wk, and the second group received the food item with no treatment. Dosage forms: intravenous solution (500 mg/100 mL), oral capsule (375 mg), oral suspension (100 mg/mL; 50 mg/mL), oral tablet (250 mg; 500 mg), oral tablet, extended release (750 mg) Metronidazole pregnancy and breastfeeding warnings, Detailed Metronidazole dosage information. Bookshelf Figure 7 : Cysts of Giardia lamblia,stained with iron- hematoxylin (A, B) and in a wet mount (C; from a patient seen in Haiti). Nitazoxanide, paromomycin, and azithromycin . A healthcare provider will give you the injection if you are unable to take the medicine by mouth. It does seems that the concern attached to this reaction is overstated. However, there is controversy around this reaction because while some studies have shown serious problems for some people taking metronidazole, others have shown the combination does not cause any problems. A. Clinton White Jr receives royalties from UpToDate and Harrison's Internal Medicine for chapters on a different subject. Thank you for taking the time to confirm your preferences. government site. No anti-infective has been found to reliably eradicate Cryptosporidium, although several drugs (e.g., paromomycin, azithromycin, nitazoxanide) appear to suppress the infection. . In some animals, particularly ruminants but also wild mammals, Giardia infection commonly occurs without overt or apparent clinical signs. Symptoms may include flushing, headaches, nausea, vomiting, and stomach cramps. When a person consumes alcohol, the body breaks it down in two steps. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Cryptosporidium are very resistant to chemical disinfectants, but steam cleaning has been shown to reduce infection, as sporulated oocysts become inactive when exposed to temperatures over 65C. 16th ed. Once inside your body, the parasite passes through your digestive tract and infects your stool. Diarrhea within 24 hours of ingestion is most likely caused by C. perfringens or B. cereus. fever. You may be contagious up to two weeks after your symptoms stop, so make sure you continue to take precautions even after you feel better. doi: 10.1371/journal.pone.0281216. Bethesda, MD 20894, Web Policies ChildrenDose is based on body weight and must be determined by your doctor. Cryptosporidiosis is a disease usually caused by the parasites Cryptosporidium hominis and C. parvum. Stool microscopy is rarely diagnostic, but the presence of red and white blood cells may signal a colonic source.4 Its primary use is identification of ova, cysts, and parasites, although antigen testing is more sensitive and specific for Giardia. acute intestinal infection due to Entamoeba histolytica. Front Cell Infect Microbiol. Continue reading. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Rapid loss of fluids from diarrhea may be especially life threatening to babies. We also searched Essential Evidence Plus, UpToDate, OVID, and the Internet, specifically focusing on information contained in the CDC and FDA websites, as well as the Cochrane library. Ask your doctor about your risk. This site needs JavaScript to work properly. Online ahead of print. Cryptosporidium parasites, which live in the intestines of humans or animals, are shed in stool. Diagnosis and control of cryptosporidiosis in farm animals. Get useful, helpful and relevant health + wellness information. Replacement of fluids and electrolytes is the critically important first step in the management of this diarrheal illness. Antiprotozoal medication can also be used to treat cryptosporidiosis in people with healthy immune systems. The best way to take care of yourself at home with cryptosporidiosis is to make sure youre staying hydrated and that your symptoms dont worsen. . This can result in an overgrowth of the candida yeast. Side effects may be more likely in older adults.